| Product Name | Patched |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTCH1 antibody; PTCH antibody; Protein patched homolog 1 antibody; PTC antibody; PTC1 antibody; |
| Product description | This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Patched. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | PTCH1 antibody PTCH antibody Protein patched homolog 1 antibody PTC antibody PTC1 antibody |
|---|---|
| Molecular Weight(MW) | 160 kDa |
| SwissProt ID | Q13635 |
|---|
| Positive Control | Brain,Cerebellum,Fetal brain,Lung, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
