| Product Name | PDZ-RhoGEF |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ARHGEF11 antibody; KIAA0380 antibody; Rho guanine nucleotide exchange factor 11 antibody; PDZ-RhoGEF antibody; |
| Product description | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. A similar protein in rat interacts with glutamate transporter EAAT4 and modulates its glutamate transport activity. Expression of the rat protein induces the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia. Two alternative transcripts encoding different isoforms have been described. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARHGEF11. AA range:198-247 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ARHGEF11 antibody KIAA0380 antibody Rho guanine nucleotide exchange factor 11 antibody PDZ-RhoGEF antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | O15085 |
|---|
| Positive Control | Brain,Epithelium,Skin, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
