| Product Name |
PFK-2 liv/tes |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
PFKFB1 antibody; F6PK antibody; PFRX antibody; 6-phosphofructo-2-kinase/fructose-2 antibody; 6-bisphosphatase 1 antibody; 6PF-2-K/Fru-2,6-P2ase 1 antibody; PFK/FBPase 1 antibody; 6PF-2-K/Fru-2,6-P2ase liver isozyme antibody; PFKFB4 antibody; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 antibody; 6PF-2-K/Fru-2,6-P2ase 4 antibody; antibody; |
| Product description |
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human PFKFB1/4. AA range:331-380 |