| Product Name | PGI2 synthase |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTGIS antibody; CYP8 antibody; CYP8A1 antibody; Prostacyclin synthase antibody; Prostaglandin I2 synthase antibody; |
| Product description | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. |
| Immunogen | Synthesized peptide derived from the C-terminal region of human PGI2 synthase. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | PTGIS antibody CYP8 antibody CYP8A1 antibody Prostacyclin synthase antibody Prostaglandin I2 synthase antibody |
|---|---|
| Molecular Weight(MW) | 57 kDa |
| SwissProt ID | Q16647 |
|---|
| Positive Control | Aorta,Brain, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
