| Product Name | PHKA1/2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PHKA1 antibody; PHKA antibody; Phosphorylase b kinase regulatory subunit alpha antibody; skeletal muscle isoform antibody; Phosphorylase kinase alpha M subunit antibody; PHKA2 antibody; PHKLA antibody; PYK antibody; Phosphorylase b kinase regulatory subunit alpha, liver isoform antibody; Phosphorylase kinase alpha L sub antibody; |
| Product description | Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript varian |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KPB1/2. AA range:31-80 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | PHKA1 antibody PHKA antibody Phosphorylase b kinase regulatory subunit alpha antibody skeletal muscle isoform antibody Phosphorylase kinase alpha M subunit antibody PHKA2 antibody PHKLA antibody PYK antibody Phosphorylase b kinase regulatory subunit alpha liver isoform antibody Phosphorylase kinase alpha L sub antibody |
|---|---|
| Molecular Weight(MW) | 137 kDa |
| Positive Control | Brain,Muscle, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
