| Product Name |
PIASx |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
PIAS2 antibody; PIASX antibody; E3 SUMO-protein ligase PIAS2 antibody; Androgen receptor-interacting protein 3 antibody; ARIP3 antibody; DAB2-interacting protein antibody; DIP antibody; Msx-interacting zinc finger protein antibody; Miz1 antibody; PIAS-NY protein antibody; Protein inhibitor of activated STAT x antibody; Protein inhibitor antibody; |
| Product description |
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human PIAS2. AA range:10-59 |