| Product Name | PIG3 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TP53I3 antibody; PIG3 antibody; Quinone oxidoreductase PIG3 antibody; Tumor protein p53-inducible protein 3 antibody; p53-induced gene 3 protein antibody; |
| Product description | The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human QORX. AA range:241-290 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TP53I3 antibody PIG3 antibody Quinone oxidoreductase PIG3 antibody Tumor protein p53-inducible protein 3 antibody p53-induced gene 3 protein antibody |
|---|---|
| Molecular Weight(MW) | 36 kDa |
| SwissProt ID | Q53FA7 |
|---|
| Positive Control | Colon cancer,Gastric mucosa,Lung carcinoma,Mammary tumor,Muscle, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
