| Product Name | Pin1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PIN1 antibody; Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody; Peptidyl-prolyl cis-trans isomerase Pin1 antibody; PPIase Pin1 antibody; Rotamase Pin1 antibody; |
| Product description | Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene., |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Pin1. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIF |
| IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | PIN1 antibody Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody Peptidyl-prolyl cis-trans isomerase Pin1 antibody PPIase Pin1 antibody Rotamase Pin1 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q13526 |
|---|
| Positive Control | Lung,Testis, |
|---|---|
| Application Notes | IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
