| Product Name | PIP5KIII |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PIKFYVE antibody; KIAA0981 antibody; PIP5K3 antibody; 1-phosphatidylinositol 3-phosphate 5-kinase antibody; Phosphatidylinositol 3-phosphate 5-kinase antibody; FYVE finger-containing phosphoinositide kinase antibody; PIKfyve antibody; Phosphatidylinositol 3-phosphate 5-kinase type III antibody; PIPkin-III antibody; Type antibody; |
| Product description | Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions, membrane trafficking, and receptor signaling by recruiting protein complexes to cell- and endosomal-membranes. Humans have multiple PtdIns proteins that differ by the degree and position of phosphorylation of the inositol ring. This gene encodes an enzyme (PIKfyve; also known as phosphatidylinositol-3-phosphate 5-kinase type III or PIPKIII) that phosphorylates the D-5 position in PtdIns and phosphatidylinositol-3-phosphate (PtdIns3P) to make PtdIns5P and PtdIns(3,5)biphosphate. The D-5 position also can be phosphorylated by type I PtdIns4P-5-kinases (PIP5Ks) that are encoded by distinct genes and preferentially phosphorylate D-4 phosphorylated PtdIns. In contrast, PIKfyve preferentially phosphorylates D-3 phosphorylated PtdIns. In addition to being a lipid kinase, PIKf |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PIP5K. AA range:71-120 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | PIKFYVE antibody KIAA0981 antibody PIP5K3 antibody 1-phosphatidylinositol 3-phosphate 5-kinase antibody Phosphatidylinositol 3-phosphate 5-kinase antibody FYVE finger-containing phosphoinositide kinase antibody PIKfyve antibody Phosphatidylinositol 3-phosphate 5-kinase type III antibody PIPkin-III antibody Type antibody |
|---|---|
| Molecular Weight(MW) | 237 kDa |
| SwissProt ID | Q9Y2I7 |
|---|
| Positive Control | Brain,Epithelium,PCR rescued clones,T-cell, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
