POT1 antibody; Protection of telomeres protein 1 antibody; hPot1 antibody; POT1-like telomere end-binding protein antibody;
Product description
This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.
Immunogen
The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
HumanMonkey
Concentration
1mg/ml
Target Information
Alternative Names
POT1 antibody Protection of telomeres protein 1 antibody hPot1 antibody POT1-like telomere end-binding protein antibody