PPM1L antibody; PP2CE antibody; Protein phosphatase 1L antibody; Protein phosphatase 1-like antibody; Protein phosphatase 2C isoform epsilon antibody; PP2C-epsilon antibody;
Product description
The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human PPM1L. AA range:119-168
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
PPM1L antibody PP2CE antibody Protein phosphatase 1L antibody Protein phosphatase 1-like antibody Protein phosphatase 2C isoform epsilon antibody PP2C-epsilon antibody