| Product Name | PRAK |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MAPKAPK5 antibody; PRAK antibody; MAP kinase-activated protein kinase 5 antibody; MAPK-activated protein kinase 5 antibody; MAPKAP kinase 5 antibody; MAPKAP-K5 antibody; MAPKAPK-5 antibody; MK-5 antibody; MK5 antibody; p38-regulated/activated protein kinase antibody; PRAK antibody; |
| Product description | The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MAPKAPK5. AA range:148-197 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | MAPKAPK5 antibody PRAK antibody MAP kinase-activated protein kinase 5 antibody MAPK-activated protein kinase 5 antibody MAPKAP kinase 5 antibody MAPKAP-K5 antibody MAPKAPK-5 antibody MK-5 antibody MK5 antibody p38-regulated/activated protein kinase antibody PRAK antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| SwissProt ID | Q8IW41 |
|---|
| Positive Control | Brain,Cervix,Pancreas,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
