| Product Name | PSMD12 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PSMD12 antibody; 26S proteasome non-ATPase regulatory subunit 12 antibody; 26S proteasome regulatory subunit RPN5 antibody; 26S proteasome regulatory subunit p55 antibody; |
| Product description | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3. Alternatively spliced transcript variants encoding |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PSMD12. AA range:151-200 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | PSMD12 antibody 26S proteasome non-ATPase regulatory subunit 12 antibody 26S proteasome regulatory subunit RPN5 antibody 26S proteasome regulatory subunit p55 antibody |
|---|---|
| Molecular Weight(MW) | 50 kDa |
| SwissProt ID | O00232 |
|---|
| Positive Control | Brain,Muscle,Platelet,Testis,Tongue, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
