| Product Name | PTP IA-2β |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTPRN2 antibody; KIAA0387 antibody; Receptor-type tyrosine-protein phosphatase N2 antibody; R-PTP-N2 antibody; Islet cell autoantigen-related protein antibody; IAR antibody; ICAAR antibody; Phogrin antibody; |
| Product description | This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PTPRN2. AA range:206-255 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | PTPRN2 antibody KIAA0387 antibody Receptor-type tyrosine-protein phosphatase N2 antibody R-PTP-N2 antibody Islet cell autoantigen-related protein antibody IAR antibody ICAAR antibody Phogrin antibody |
|---|---|
| Molecular Weight(MW) | 111 kDa |
| SwissProt ID | Q92932 |
|---|
| Positive Control | Amygdala,Brain,Fetal brain,Pancreas, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
