| Product Name | Rabaptin-5α |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RABEP1 antibody; RAB5EP antibody; RABPT5 antibody; RABPT5A antibody; Rab GTPase-binding effector protein 1 antibody; Rabaptin-4 antibody; Rabaptin-5 antibody; Rabaptin-5alpha antibody; Renal carcinoma antigen NY-REN-17 antibody; |
| Product description | Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity. Belongs to the rabaptin family. subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RABEP1. AA range:549-598 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | RABEP1 antibody RAB5EP antibody RABPT5 antibody RABPT5A antibody Rab GTPase-binding effector protein 1 antibody Rabaptin-4 antibody Rabaptin-5 antibody Rabaptin-5alpha antibody Renal carcinoma antigen NY-REN-17 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q15276 |
|---|
| Positive Control | Cervix carcinoma,Epithelium,Fetal brain cortex,Kidney,Plate |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
