| Product Name | Rad51B |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAD51B antibody; RAD51L1 antibody; REC2 antibody; DNA repair protein RAD51 homolog 2 antibody; R51H2 antibody; RAD51 homolog B antibody; Rad51B antibody; RAD51-like protein 1 antibody; |
| Product description | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAD51L1. AA range:201-250 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseMonkey |
| Concentration | 1mg/ml |
| Alternative Names | RAD51B antibody RAD51L1 antibody REC2 antibody DNA repair protein RAD51 homolog 2 antibody R51H2 antibody RAD51 homolog B antibody Rad51B antibody RAD51-like protein 1 antibody |
|---|---|
| Molecular Weight(MW) | 45 kDa |
| SwissProt ID | O15315 |
|---|
| Positive Control | Lung,Neuroblastoma, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
