| Product Name | Rad51C |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAD51C antibody; RAD51L2 antibody; DNA repair protein RAD51 homolog 3 antibody; R51H3 antibody; RAD51 homolog C antibody; RAD51-like protein 2 antibody; |
| Product description | This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAD51C. AA range:161-210 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMonkey |
| Concentration | 1mg/ml |
| Alternative Names | RAD51C antibody RAD51L2 antibody DNA repair protein RAD51 homolog 3 antibody R51H3 antibody RAD51 homolog C antibody RAD51-like protein 2 antibody |
|---|---|
| Molecular Weight(MW) | 50 kDa |
| SwissProt ID | O43502 |
|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
