| Product Name | Rag A/B |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RRAGA antibody; Ras-related GTP-binding protein A antibody; Rag A antibody; RagA antibody; Adenovirus E3 14.7 kDa-interacting protein 1 antibody; FIP-1 antibody; RRAGB antibody; Ras-related GTP-binding protein B antibody; Rag B antibody; RagB antibody; |
| Product description | Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14. 7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Belongs to the GTR/RAG GTP-binding protein family. subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state. Colocalizes in vivo with adenovirus E3-14. 7K mainly to the cytoplasm especially near the nuclear membrane and in discrete foci on or near the plasma membrane. subunit:Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14. 7 kDa protein. tissue specificity:Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RRAGA/B. AA range:264-313 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | RRAGA antibody Ras-related GTP-binding protein A antibody Rag A antibody RagA antibody Adenovirus E3 14.7 kDa-interacting protein 1 antibody FIP-1 antibody RRAGB antibody Ras-related GTP-binding protein B antibody Rag B antibody RagB antibody |
|---|---|
| Molecular Weight(MW) | 34 kDa |
| Positive Control | Brain,Fetal brain,Ovary, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
