RCC2 antibody; KIAA1470 antibody; TD60 antibody; Protein RCC2 antibody; RCC1-like protein TD-60 antibody; Telophase disk protein of 60 kDa antibody;
Product description
Required for completion of mitosis and cytokinesis. May function as a guanine nucleotide exchange factor for the small GTPase RAC1. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Contains 7 RCC1 repeats. subcellular location:Appears in the nucleus at G2, then concentrates at the inner centromere region of chromosomes during prophase. Redistributes to the midzone of the mitotic spindle during anaphase. Here, the protein covers the entire equatorial diameter from cortex to cortex. subunit:Binds preferentially to the nucleotide-free form of RAC1. Interacts with microtubules.
Immunogen
The antiserum was produced against synthesized peptide derived from human RCC2. AA range:473-522
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:500-1:2000 IHC:1:100-1:300
Species Reactivity
HumanMouse
Concentration
1mg/ml
Target Information
Alternative Names
RCC2 antibody KIAA1470 antibody TD60 antibody Protein RCC2 antibody RCC1-like protein TD-60 antibody Telophase disk protein of 60 kDa antibody