| Product Name | Reg IV |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | REG4 antibody; GISP antibody; RELP antibody; Regenerating islet-derived protein 4 antibody; REG-4 antibody; Gastrointestinal secretory protein antibody; REG-like protein antibody; Regenerating islet-derived protein IV antibody; Reg IV antibody; |
| Product description | May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium. induction:Up-regulated by mucosal injury from active Crohn's disease or ulcerative colitis. Up-regulated in colorectal tumors. Up-regulated in epithelial cells at regenerating margins of peptic ulcers in the stomach and duodenum. online information:Regenerating protein IV,Contains 1 C-type lectin domain. tissue specificity:Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentialy expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells. |
| Immunogen | Synthesized peptide derived from the Internal region of human Reg IV. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | REG4 antibody GISP antibody RELP antibody Regenerating islet-derived protein 4 antibody REG-4 antibody Gastrointestinal secretory protein antibody REG-like protein antibody Regenerating islet-derived protein IV antibody Reg IV antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q9BYZ8 |
|---|
| Positive Control | Colon,Colon cancer, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
