| Product Name | Repac |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RAPGEF5 antibody; GFR antibody; KIAA0277 antibody; MRGEF antibody; Rap guanine nucleotide exchange factor 5 antibody; Guanine nucleotide exchange factor for Rap1 antibody; M-Ras-regulated Rap GEF antibody; MR-GEF antibody; Related to Epac antibody; Repac antibody; |
| Product description | Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al. 2000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RAPGEF5. AA range:431-480 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | RAPGEF5 antibody GFR antibody KIAA0277 antibody MRGEF antibody Rap guanine nucleotide exchange factor 5 antibody Guanine nucleotide exchange factor for Rap1 antibody M-Ras-regulated Rap GEF antibody MR-GEF antibody Related to Epac antibody Repac antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| SwissProt ID | Q92565 |
|---|
| Positive Control | Brain,Lymph node, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
