RGS10 antibody; Regulator of G-protein signaling 10 antibody; RGS10 antibody;
Product description
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human RGS10. AA range:80-129
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:500-1:2000 IHC:1:100-1:300
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
RGS10 antibody Regulator of G-protein signaling 10 antibody RGS10 antibody