| Product Name | RGS14 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | RGS14 antibody; Regulator of G-protein signaling 14 antibody; RGS14 antibody; |
| Product description | This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RGS14. AA range:125-174 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | RGS14 antibody Regulator of G-protein signaling 14 antibody RGS14 antibody |
|---|---|
| Molecular Weight(MW) | 65 kDa |
| SwissProt ID | O43566 |
|---|
| Positive Control | Brain,Caudate nucleus,Colon, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
