RGS7 antibody; Regulator of G-protein signaling 7 antibody; RGS7 antibody;
Product description
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations. PTM:Palmitoylated. PTM:Phosphorylation and subsequent interaction with 14-3-3 proteins inhibits GAP activity. Contains 1 DEP domain. Contains 1 G protein gamma domain. Contains 1 RGS domain. subunit:Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). Interacts with 14-3-3 protein Tau and SNAP25BP.
Immunogen
The antiserum was produced against synthesized peptide derived from human RGS7. AA range:155-204
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
RGS7 antibody Regulator of G-protein signaling 7 antibody RGS7 antibody