RHOH antibody; ARHH antibody; TTF antibody; Rho-related GTP-binding protein RhoH antibody; GTP-binding protein TTF antibody; Translocation three four protein antibody;
Product description
The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human RhoH. AA range:141-190
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHCIF
WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
RHOH antibody ARHH antibody TTF antibody Rho-related GTP-binding protein RhoH antibody GTP-binding protein TTF antibody Translocation three four protein antibody