ELAC2 antibody; HPC2 antibody; Zinc phosphodiesterase ELAC protein 2 antibody; ElaC homolog protein 2 antibody; Heredity prostate cancer protein 2 antibody; Ribonuclease Z 2 antibody; RNase Z 2 antibody; tRNA 3 endonuclease 2 antibody; tRNase Z 2 antibody;
Product description
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human ELAC2. AA range:161-210
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC
IHC:1:100-1:300
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
ELAC2 antibody HPC2 antibody Zinc phosphodiesterase ELAC protein 2 antibody ElaC homolog protein 2 antibody Heredity prostate cancer protein 2 antibody Ribonuclease Z 2 antibody RNase Z 2 antibody tRNA 3 endonuclease 2 antibody tRNase Z 2 antibody