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OM635961
Discount Price
OM635961-100ul
1~2 Week
100ul
OM635961-50ul
50ul
OM635961-20ul
20ul
1~2 Week
Product Profile
Product Name RNase Z2
Antibody Type Primary Antibodies
Antigen Alias ELAC2 antibody; HPC2 antibody; Zinc phosphodiesterase ELAC protein 2 antibody; ElaC homolog protein 2 antibody; Heredity prostate cancer protein 2 antibody; Ribonuclease Z 2 antibody; RNase Z 2 antibody; tRNA 3 endonuclease 2 antibody; tRNase Z 2 antibody;
Product description The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen The antiserum was produced against synthesized peptide derived from human ELAC2. AA range:161-210
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHC
IHC:1:100-1:300
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names ELAC2 antibody
HPC2 antibody
Zinc phosphodiesterase ELAC protein 2 antibody
ElaC homolog protein 2 antibody
Heredity prostate cancer protein 2 antibody
Ribonuclease Z 2 antibody
RNase Z 2 antibody
tRNA 3 endonuclease 2 antibody
tRNase Z 2 antibody
Molecular Weight(MW) kDa
Database Links
SwissProt ID Q9BQ52
Positive Control Epithelium,Hippocampus,Liver,Lung,Teratocarcinoma,Thalamus,
Application Notes IHC:1:100-1:300
Additional Information
Form Liquid
Storage Instructions Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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