| Product Name |
RO60 |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
TROVE2 antibody; RO60 antibody; SSA2 antibody; 60 kDa SS-A/Ro ribonucleoprotein antibody; 60 kDa Ro protein antibody; 60 kDa ribonucleoprotein Ro antibody; RoRNP antibody; Ro 60 kDa autoantigen antibody; Sjoegren syndrome antigen A2 antibody; Sjoegren syndrome type A antigen antibody; SS-A antibody; TROVE domain family member 2 antibody; |
| Product description |
disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign. RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Belongs to the Ro 60 kDa family. Contains 1 TROVE domain. subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human TROVE2. AA range:311-360 |