| Product Name | S2P |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MBTPS2 antibody; S2P antibody; Membrane-bound transcription factor site-2 protease antibody; Endopeptidase S2P antibody; Sterol regulatory element-binding proteins intramembrane protease antibody; SREBPs intramembrane protease antibody; |
| Product description | This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response., |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MBTPS2. AA range:301-350 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IF |
| IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | MBTPS2 antibody S2P antibody Membrane-bound transcription factor site-2 protease antibody Endopeptidase S2P antibody Sterol regulatory element-binding proteins intramembrane protease antibody SREBPs intramembrane protease antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | O43462 |
|---|
| Positive Control | Fibroblast, |
|---|---|
| Application Notes | IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
