| Product Name | SAP 49 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SF3B4 antibody; SAP49 antibody; Splicing factor 3B subunit 4 antibody; Pre-mRNA-splicing factor SF3b 49 kDa subunit antibody; SF3b50 antibody; Spliceosome-associated protein 49 antibody; SAP 49 antibody; |
| Product description | This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SF3B4. AA range:61-110 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | SF3B4 antibody SAP49 antibody Splicing factor 3B subunit 4 antibody Pre-mRNA-splicing factor SF3b 49 kDa subunit antibody SF3b50 antibody Spliceosome-associated protein 49 antibody SAP 49 antibody |
|---|---|
| Molecular Weight(MW) | 55 kDa |
| SwissProt ID | Q15427 |
|---|
| Positive Control | Ovarian carcinoma,Skin,Testis,Thymus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
