| Product Name | Sck |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SHC2 antibody; SCK antibody; SHCB antibody; SHC-transforming protein 2 antibody; Protein Sck antibody; SHC-transforming protein B antibody; Src homology 2 domain-containing-transforming protein C2 antibody; SH2 domain protein C2 antibody; |
| Product description | domain:The PID domain mediates binding to the TrkA receptor. Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons. miscellaneous:PubMed:15057824 has shown that SHC2 is poorly phosphorylated by the Trk receptors, in opposite to PubMed:12006576. PTM:Phosphorylated on tyrosines by the Trk receptors. Contains 1 PID domain. Contains 1 SH2 domain. subunit:Interacts with the Trk receptors in a phosphotyrosine-dependent manner and MEGF12. Once activated, binds to GRB2. tissue specificity:Expressed in brain. Expressed at high level in the hypothalamus and at low level in the caudate nucleus. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SHC2. AA range:261-310 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml |
| Alternative Names | SHC2 antibody SCK antibody SHCB antibody SHC-transforming protein 2 antibody Protein Sck antibody SHC-transforming protein B antibody Src homology 2 domain-containing-transforming protein C2 antibody SH2 domain protein C2 antibody |
|---|---|
| Molecular Weight(MW) | 59 kDa |
| SwissProt ID | P98077 |
|---|
| Positive Control | Fetal brain,Platelet, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
