| Product Name | SENP6 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SENP6 antibody; KIAA0797 antibody; SSP1 antibody; SUSP1 antibody; FKSG6 antibody; Sentrin-specific protease 6 antibody; SUMO-1-specific protease 1 antibody; Sentrin/SUMO-specific protease SENP6 antibody; |
| Product description | Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al. 2000). SENPs also display isopeptidase activity for |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SENP6. AA range:1042-1091 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SENP6 antibody KIAA0797 antibody SSP1 antibody SUSP1 antibody FKSG6 antibody Sentrin-specific protease 6 antibody SUMO-1-specific protease 1 antibody Sentrin/SUMO-specific protease SENP6 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q9GZR1 |
|---|
| Positive Control | Brain,Epithelium,Testis,Tongue,Whole embryo, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
