| Product Name |
SETMAR |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
SETMAR antibody; Histone-lysine N-methyltransferase SETMAR antibody; SET domain and mariner transposase fusion gene-containing protein antibody; HsMar1 antibody; Metnase antibody; |
| Product description |
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human SETMAR. AA range:350-400 |
