| Product Name | Sgo2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SGOL2 antibody; Shugoshin-like 2 antibody; Shugoshin-2 antibody; Sgo2 antibody; Tripin antibody; |
| Product description | During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis (By similarity). May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. sequence caution:Contaminating sequence. Potential poly-A sequence. Belongs to the shugoshin family. subcellular location:In Hela cells, localizes at centromeres throughout prophase until metaphase and disappears at anaphase. subunit:Directly interacts with PPP2CA. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SGOL2. AA range:681-730 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SGOL2 antibody Shugoshin-like 2 antibody Shugoshin-2 antibody Sgo2 antibody Tripin antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q562F6 |
|---|
| Positive Control | Epithelium,Lymph,Testis,Uterus, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
