| Product Name | Siah-1/2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SIAH1 antibody; HUMSIAH antibody; E3 ubiquitin-protein ligase SIAH1 antibody; Seven in absentia homolog 1 antibody; Siah-1 antibody; Siah-1a antibody; SIAH2 antibody; E3 ubiquitin-protein ligase SIAH2 antibody; Seven in absentia homolog 2 antibody; Siah-2 antibody; hSiah2 antibody; |
| Product description | This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SIAH1. AA range:181-230 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | SIAH1 antibody HUMSIAH antibody E3 ubiquitin-protein ligase SIAH1 antibody Seven in absentia homolog 1 antibody Siah-1 antibody Siah-1a antibody SIAH2 antibody E3 ubiquitin-protein ligase SIAH2 antibody Seven in absentia homolog 2 antibody Siah-2 antibody hSiah2 antibody |
|---|---|
| Molecular Weight(MW) | 34 kDa |
| Positive Control | Brain,Fetal brain,Intestinal epithelium,Pancreas,Retina,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
