| Product Name | SKI-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MBTPS1 antibody; KIAA0091 antibody; S1P antibody; SKI1 antibody; Membrane-bound transcription factor site-1 protease antibody; Endopeptidase S1P antibody; Subtilisin/kexin-isozyme 1 antibody; SKI-1 antibody; |
| Product description | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. |
| Immunogen | Synthesized peptide derived from SKI-1 . at AA range: 180-260 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | MBTPS1 antibody KIAA0091 antibody S1P antibody SKI1 antibody Membrane-bound transcription factor site-1 protease antibody Endopeptidase S1P antibody Subtilisin/kexin-isozyme 1 antibody SKI-1 antibody |
|---|---|
| Molecular Weight(MW) | 20 kDa |
| SwissProt ID | Q14703 |
|---|
| Positive Control | Bone marrow,Myeloid,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
