| Product Name | SMG7 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SMG7 antibody; C1orf16 antibody; EST1C antibody; KIAA0250 antibody; Protein SMG7 antibody; EST1-like protein C antibody; SMG-7 homolog antibody; hSMG-7 antibody; |
| Product description | This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex. The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1. The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex. This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SMG7. AA range:521-570 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SMG7 antibody C1orf16 antibody EST1C antibody KIAA0250 antibody Protein SMG7 antibody EST1-like protein C antibody SMG-7 homolog antibody hSMG-7 antibody |
|---|---|
| Molecular Weight(MW) | 127 kDa |
| SwissProt ID | Q92540 |
|---|
| Positive Control | Bone marrow,Brain,Epithelium,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
