| Product Name | SnoN |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SKIL antibody; SNO antibody; Ski-like protein antibody; Ski-related oncogene antibody; Ski-related protein antibody; |
| Product description | The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SKIL. AA range:616-665 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | SKIL antibody SNO antibody Ski-like protein antibody Ski-related oncogene antibody Ski-related protein antibody |
|---|---|
| Molecular Weight(MW) | 77 kDa |
| SwissProt ID | P12757 |
|---|
| Positive Control | Kidney,Myoblast,Placenta,Umbilical vein endothelial cell, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
