| Product Name | SOCS-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SOCS1 antibody; SSI1 antibody; TIP3 antibody; Suppressor of cytokine signaling 1 antibody; SOCS-1 antibody; JAK-binding protein antibody; JAB antibody; STAT-induced STAT inhibitor 1 antibody; SSI-1 antibody; Tec-interacting protein 3 antibody; TIP-3 antibody; |
| Product description | This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SOCS-1. AA range:49-98 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFWBIHC |
| IF:1:50-200 WB IHC:1:50-300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | SOCS1 antibody SSI1 antibody TIP3 antibody Suppressor of cytokine signaling 1 antibody SOCS-1 antibody JAK-binding protein antibody JAB antibody STAT-induced STAT inhibitor 1 antibody SSI-1 antibody Tec-interacting protein 3 antibody TIP-3 antibody |
|---|---|
| Molecular Weight(MW) | 38 kDa |
| SwissProt ID | O15524 |
|---|
| Positive Control | B-cell,Lung,Myeloid leukemia cell,T-cell lymphoma, |
|---|---|
| Application Notes | IF:1:50-200 WB IHC:1:50-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
