| Product Name | SP-100 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SP100 antibody; Nuclear autoantigen Sp-100 antibody; Lysp100b antibody; Nuclear dot-associated Sp100 protein antibody; Speckled 100 kDa antibody; |
| Product description | This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein. |
| Immunogen | Synthesized peptide derived from SP-100 . at AA range: 250-330 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | SP100 antibody Nuclear autoantigen Sp-100 antibody Lysp100b antibody Nuclear dot-associated Sp100 protein antibody Speckled 100 kDa antibody |
|---|---|
| Molecular Weight(MW) | 100 kDa |
| SwissProt ID | P23497 |
|---|
| Positive Control | Cervix carcinoma,Epithelium,Kidney,Liver,Lymphoma,Mammary cancer,Placenta,Salivary |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
