| Product Name | Splicing factor 1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SF1 antibody; ZFM1 antibody; ZNF162 antibody; Splicing factor 1 antibody; Mammalian branch point-binding protein antibody; BBP antibody; mBBP antibody; Transcription factor ZFM1 antibody; Zinc finger gene in MEN1 locus antibody; Zinc finger protein 162 antibody; |
| Product description | This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SF1. AA range:48-97 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | SF1 antibody ZFM1 antibody ZNF162 antibody Splicing factor 1 antibody Mammalian branch point-binding protein antibody BBP antibody mBBP antibody Transcription factor ZFM1 antibody Zinc finger gene in MEN1 locus antibody Zinc finger protein 162 antibody |
|---|---|
| Molecular Weight(MW) | 68 kDa |
| SwissProt ID | Q15637 |
|---|
| Positive Control | Bone,Brain,Brain cortex,Cerebellum,Cerebrum,Cervix carcinoma,Epithelium,Eye,Fetal liver,Kid |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
