| Product Name | ST5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ST5 antibody; DENND2B antibody; HTS1 antibody; Suppression of tumorigenicity 5 protein antibody; DENN domain-containing protein 2B antibody; HeLa tumor suppression 1 antibody; |
| Product description | This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ST5. AA range:411-460 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | ST5 antibody DENND2B antibody HTS1 antibody Suppression of tumorigenicity 5 protein antibody DENN domain-containing protein 2B antibody HeLa tumor suppression 1 antibody |
|---|---|
| Molecular Weight(MW) | 126 kDa |
| SwissProt ID | P78524 |
|---|
| Positive Control | Bladder,Brain,Epithelium,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
