SS18 antibody; SSXT antibody; SYT antibody; Protein SSXT antibody; Protein SYT antibody; Synovial sarcoma translocated to X chromosome protein antibody;
Product description
disease:A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11. 2;q11. 2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). Belongs to the SS18 family. tissue specificity:Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.
Immunogen
The antiserum was produced against synthesized peptide derived from human SSXT. AA range:1-50
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHC
WB:1:500-1:2000 IHC:1:100-1:300
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
SS18 antibody SSXT antibody SYT antibody Protein SSXT antibody Protein SYT antibody Synovial sarcoma translocated to X chromosome protein antibody