| Product Name | TAFI |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CPB2 antibody; Carboxypeptidase B2 antibody; Carboxypeptidase U antibody; CPU antibody; Plasma carboxypeptidase B antibody; pCPB antibody; Thrombin-activable fibrinolysis inhibitor antibody; TAFI antibody; |
| Product description | Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CPB2. AA range:321-370 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CPB2 antibody Carboxypeptidase B2 antibody Carboxypeptidase U antibody CPU antibody Plasma carboxypeptidase B antibody pCPB antibody Thrombin-activable fibrinolysis inhibitor antibody TAFI antibody |
|---|---|
| Molecular Weight(MW) | 48 kDa |
| SwissProt ID | Q96IY4 |
|---|
| Positive Control | Liver,Plasma,Skeletal muscle, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
