| Product Name | TFIIH p44 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GTF2H2 antibody; BTF2P44 antibody; General transcription factor IIH subunit 2 antibody; Basic transcription factor 2 44 kDa subunit antibody; BTF2 p44 antibody; General transcription factor IIH polypeptide 2 antibody; TFIIH basal transcription factor complex p44 subunit antibody; |
| Product description | This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of t |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TF2H2. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | GTF2H2 antibody BTF2P44 antibody General transcription factor IIH subunit 2 antibody Basic transcription factor 2 44 kDa subunit antibody BTF2 p44 antibody General transcription factor IIH polypeptide 2 antibody TFIIH basal transcription factor complex p44 subunit antibody |
|---|---|
| Molecular Weight(MW) | 62 kDa |
| SwissProt ID | Q13888 |
|---|
| Positive Control | Brain,Liver,Pituitary tumor,Pre-B cell,Skin,Stomach,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
