| Product Name | TGIF |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TGIF1 antibody; TGIF antibody; Homeobox protein TGIF1 antibody; 5'-TG-3'-interacting factor 1 antibody; |
| Product description | The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provide |
| Immunogen | Synthesized peptide derived from the C-terminal region of human TGIF. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | TGIF1 antibody TGIF antibody Homeobox protein TGIF1 antibody 5'-TG-3'-interacting factor 1 antibody |
|---|---|
| Molecular Weight(MW) | 43 kDa |
| SwissProt ID | Q15583 |
|---|
| Positive Control | Brain,Liver,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
