| Product Name | TGR5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GPBAR1 antibody; TGR5 antibody; G-protein coupled bile acid receptor 1 antibody; G-protein coupled receptor GPCR19 antibody; hGPCR19 antibody; Membrane-type receptor for bile acids antibody; M-BAR antibody; hBG37 antibody; BG37 antibody; |
| Product description | This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human GPBAR. AA range:11-60 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IF |
| IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GPBAR1 antibody TGR5 antibody G-protein coupled bile acid receptor 1 antibody G-protein coupled receptor GPCR19 antibody hGPCR19 antibody Membrane-type receptor for bile acids antibody M-BAR antibody hBG37 antibody BG37 antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q8TDU6 |
|---|
| Positive Control | Pancreas,Placenta,Spleen, |
|---|---|
| Application Notes | IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
