| Product Name | TLE2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TLE2 antibody; Transducin-like enhancer protein 2 antibody; Enhancer of split groucho-like protein 2 antibody; ESG2 antibody; |
| Product description | Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Belongs to the WD repeat Groucho/TLE family. Contains 6 WD repeats. subunit:Homooligomer and heterooligomer with other family members. Binds LEF1, TCF7, TCF7L1, TCF7L2, UTY, HES1 and HES5. tissue specificity:In all tissues examined, mostly in heart, brain, and muscle. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TLE2. AA range:211-260 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | TLE2 antibody Transducin-like enhancer protein 2 antibody Enhancer of split groucho-like protein 2 antibody ESG2 antibody |
|---|---|
| Molecular Weight(MW) | 110 kDa |
| SwissProt ID | Q04725 |
|---|
| Positive Control | Bladder,Fetal brain,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
