| Product Name | TMC8 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TMC8 antibody; EVER2 antibody; EVIN2 antibody; Transmembrane channel-like protein 8 antibody; Epidermodysplasia verruciformis protein 2 antibody; |
| Product description | Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25. 3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TMC8. AA range:601-650 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | TMC8 antibody EVER2 antibody EVIN2 antibody Transmembrane channel-like protein 8 antibody Epidermodysplasia verruciformis protein 2 antibody |
|---|---|
| Molecular Weight(MW) | 81 kDa |
| SwissProt ID | Q8IU68 |
|---|
| Positive Control | Blood,Epithelium,Spleen,Thymus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
