| Product Name | TNF-IP 8 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFAIP8 antibody; Tumor necrosis factor alpha-induced protein 8 antibody; TNF alpha-induced protein 8 antibody; Head and neck tumor and metastasis-related protein antibody; MDC-3.13 antibody; NF-kappa-B-inducible DED-containing protein antibody; NDED antibody; SCC-S2 antibody; TNF-induced protein GG2-1 antibody; |
| Product description | developmental stage:Expressed at high levels in the fetal liver, lung and kidney. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation. induction:By nuclear factor-KB (NF-KB) and TNF. Induction by TNF depends upon activation of NF-KB. Belongs to the TNFAIP8 family. tissue specificity:Expressed at high levels in the spleen, lymph node, thymus, thyroid, bone marrow and placenta. Expressed at high levels both in various tumor tissues, unstimulated and cytokine-activated cultured cells. Expressed at low levels in the spinal cord, ovary, lung, adrenal glands, heart, brain, testis and skeletal muscle. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TFIP8. AA range:31-80 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | TNFAIP8 antibody Tumor necrosis factor alpha-induced protein 8 antibody TNF alpha-induced protein 8 antibody Head and neck tumor and metastasis-related protein antibody MDC-3.13 antibody NF-kappa-B-inducible DED-containing protein antibody NDED antibody SCC-S2 antibody TNF-induced protein GG2-1 antibody |
|---|---|
| Molecular Weight(MW) | 23 kDa |
| SwissProt ID | O95379 |
|---|
| Positive Control | Brain,Heart,Placenta,Umbilical vein,Urinary bladder, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
