| Product Name | TRADD |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRADD antibody; Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody; TNFR1-associated DEATH domain protein antibody; TNFRSF1A-associated via death domain antibody; |
| Product description | The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TRADD. AA range:251-300 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseMonkey |
| Concentration | 1mg/ml |
| Alternative Names | TRADD antibody Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody TNFR1-associated DEATH domain protein antibody TNFRSF1A-associated via death domain antibody |
|---|---|
| Molecular Weight(MW) | 34 kDa |
| SwissProt ID | Q15628 |
|---|
| Positive Control | Pancreas, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
